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- Postdoctoral Fellow Retina Biochemistry and Clinical Disease Modeling Laboratory
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Postdoctoral Fellow - Retina Biochemistry & Clinical Disease Modeling Laboratory
The UCLA Stein Eye Institute and Department of Ophthalmology invite applications for postdoctoral scholars to work on basic science and translational research projects in The Retina Biochemistry & Clinical Disease Modeling Laboratory. Radu group focuses on studying the retinal pigment epithelium (RPE) in normal and pathological status pertinent to Stargardt disease and age-related macular degeneration.
Research: Current studies are directed towards understanding the intercellular organelle dynamics in the RPE centered on lysosomes maturation, recycling of retinoids and lipids relevant to cell bioenergetics (mitochondria), and identification of complement-mediated signaling pathways in aging and disease status. Projects will include in vivo studies utilizing novel mouse models and in vitro biochemical and electrophysiological approaches to investigate disease pathology in a "disease-in-a-dish" model. Experiments will involve cutting-edge cell and molecular biology techniques including differentiation of iPSCs and iPSC-derived RPE cells, spatial transcriptomes/ multiomics analysis, andadvanced microscopy imaging tools.
Qualifications: The position is for a highly motivated PhD, MD, or MD/PhD who aims to develop an independent research career. The postdoctoral fellow will lead research projects, execute experiments and analyze data, write manuscripts and present at scientific meetings.
Requirements
Apply: Interested applicants should email an updated CV, complete contact information for 3 references, cover letter describing published and ongoing work, and a statement of future research interest (1-2 pages) to: Roxana Radu (radu@jsei.ucla.edu).
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